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While seeking justice for the murders that took place in the first film, Zoey (Taylor Russell) and Ben (Logan Miller) find themselves thrust into a new escape room with four strangers while riding the train. The group soon realizes that they have all played the game before and there was a special reason why each person survived. The players then work together to survive the life-threatening challenges that are created for them and the trailer ends with two of the women escaping; however, they are not free just yet.